Research

Anti-N-methyl-D-aspartate receptor encephalitis: A targeted review of clinical presentation, diagnosis, and approaches to psychopharmacologic management February 28, 2014

Anti-N-methyl-D-aspartate receptor encephalitis: A targeted review of clinical presentation, diagnosis, and approaches to psychopharmacologic management Kruse et al Annals of Clinical Psychiatry. 2014 Feb;26(1):e1-9 https://www.researchgate.net/profile/Michael_Davis27/publication/260118368_Anti-N-methyl-D-aspartate_receptor_encephalitis_A_targeted_review_of_clinical_presentation_diagnosis_and_approaches_to_psychopharmacologic_management/links/559b423708ae5d8f39380611/Anti-N-methyl-D-aspartate-receptor-encephalitis-A-targeted-review-of-clinical-presentation-diagnosis-and-approaches-to-psychopharmacologic-management.pdf Anti-N-methyl-d-aspartate receptor encephalitis was formally described in 2007 and includes a range of psychiatric and neurologic symptoms. Most patients with anti-NMDAR encephalitis initially present to psychiatrists for diagnosis and treatment. […]

Anti-N-Methyl-D-Aspartate Receptor Encephalitis: A new challenging entity for consultation-liaison psychiatrist May 30, 2016

Anti-N-Methyl-D-Aspartate Receptor Encephalitis: A new challenging entity for consultation-liaison psychiatrist Maccaferri et al Brain Disord Ther 2016 May; 5(2):215 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4959779/ Anti-N-methyl-D-aspartate receptor encephalitis is a relatively newly identified autoimmune neuropsychiatric disorder that predominantly affects children and young adults. Although psychiatric symptoms are highly prevalent and frequently severe, it has mainly been reported in neurological, but […]

Treatment of autoimmune encephalitis with immune based therapies June 6, 2017

The Journal of Neurology, Neuroscience, and Psychiatry reports on autoimmune encephalitis patients treated with immune based therapy including rituximab.  Authors Dowland F, Swayne A, Bhuta S, et. al. discuss three cases and conclude, “The field of neuro-immunology has seen a plethora of newly discovered autoantibodies, yet there remain a significant number of patients, with features suggestive […]

Herpes simplex virus further explored in AE August 4, 2018

Many autoimmune encephalitis survivors and family members long to know what caused the illness. Some causes are known, some are not. Among the known causes of anti-NMDA AE are ovarian teratomas and a few viruses, particularly the herpes simplex virus. Studies have shown some patients who develop herpes simplex encephalitis (HSE) go on to develop […]

Calling all with a history of anti-NMDAR encephalitis to participate in a study! May 3, 2019

We would like to invite all individuals with a history of anti-NMDA receptor encephalitis (age 15-60 years at the time of symptom onset) to participate in a study of language. The AE Alliance is honored to be participating in a study led by Dr. Anusha Yekoshumar and medical student Kelsey Martin at The Icahn School […]

Autism Associated with Anti-NMDAR Encephalitis June 25, 2020

Autism, or autism spectrum disorder (ASD), refers to a broad range of conditions characterized by challenges with social skills, repetitive behaviors, speech, and nonverbal communication. There are many subtypes of autism, most influenced by a combination of genetic and environmental factors. The current prevalence of ASD is estimated to be 1.5% or higher in developed […]

Anti-N-Methyl-D-Aspartate Receptor (NMDAR) Encephalitis in Children and Adolescents February 27, 2021

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2826225/

Autoantibodies associated with diseases of the CNS: new developments and future challenges February 27, 2021

http://www.thelancet.com/journals/laneur/article/PIIS1474-4422(11)70096-5/fulltext

Extreme delta brush: a unique EEG pattern in adults with anti-NMDA receptor encephalitis February 27, 2021

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3525298/

Utility of an immunotherapy trial in evaluating patients with presumed autoimmune epilepsy February 27, 2021

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4013813/