Research

Anti-NMDA Receptor Encephalitis in Psychiatry Kayser et al. Curr Psychiatry Rev. 2011; 7(3):189-193. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3983958/ “Anti-NMDA receptor encephalitis is an autoimmune disorder in which antibodies attack NMDA (N-methyl-D-aspartate)-type glutamate receptors at central neuronal synapses. Symptoms include a highly characteristic set of neurologic deficits, but also prominent psychiatric manifestations that often bring mental health professionals into the […]

A newly released precis provides clear diagnostic criteria for autoimmune encephalitis. This effort, lead by Dr. Domingo Escudero, Dr. Francesc Graus and Dr. Josep Dalmau, summarizes the Lancet Neurology article “A clinical approach to autoimmune encephalitis“. The Lancet Neurology article  provides the first broadly accepted criteria for diagnosing autoimmune encephalitis.  A previous AE Alliance blog reviewed the article and it’s connection to the first International […]

In many areas of medicine, treatments are increasingly becoming targeted in a way that benefits patients. This is happening in fields ranging from oncology to neurological disease. In this month’s Neurology Now, treatment for autoimmune encephalitis is being cited as one area where “precision medicine” holds promise for better and targeted treatments according to antibody […]

Despite much study centered around the antibodies that cause autoimmune encephalitis, there are still many unanswered questions. One of them is exactly how the severe symptoms of this disease are produced. Physicians conducting research in Berlin, Germany and Jerusalem, Israel have together conducted an observational study of patients with anti-NMDA receptor AE as compared to […]

A group of researchers from the Autoimmune Neurology Group at the University of Oxford led by Dr. Sarosh Irani,  recently published an article in the Lancet Psychiatry, noting that a focus on the psychopathology is likely the most effective way to promote prompt recognition of NMDAR-antibody encephalitis. NMDAR-antibody encephalitis is an autoantibody-mediated disease that typically presents […]

Since December 2019, almost 13.5 million cases and 581,103 deaths due to the coronavirus have been reported worldwide, according to the Johns Hopkins Coronavirus Resource Center. There are many papers published on COVID-19 and its consequences, and we, at AE Alliance, are especially interested in how the coronavirus affects the brain. We wanted to share […]

https://journals.lww.com/cogbehavneurol/Abstract/2009/03000/Successful_Treatment_of_Acute_Autoimmune_Limbic.7.aspx

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3705177/

https://onlinelibrary.wiley.com/doi/abs/10.1002/ana.23577

https://link.springer.com/article/10.1007%2Fs11910-014-0476-2