Category: Research

Herpes simplex virus further explored in AE

Many autoimmune encephalitis survivors and family members long to know what caused the illness. Some causes are known, some are not. Among the known causes of anti-NMDA AE are ovarian teratomas and a few viruses, particularly the herpes simplex virus. Studies have shown some patients who develop herpes simplex encephalitis (HSE) go on to develop …

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Incidence of AE estimated by Mayo study

Autoimmune encephalitis experts at the Mayo Clinic published the first population-based study of AE in an effort to determine the incidence of the disease. The researchers found that in the last decade approximately 1 in every 100,000 people develop AE each year. This translates into approximately 4,000 new AE cases in the US annually and …

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Long-term neurobehavioral outcomes in Autoimmune Encephalitis

One of the first studies on long-term neurobehavioral outcomes in patients affected by AE will be presented by Anusha Yeshokumar, MD, during the upcoming Encephalitis Society meeting in London. This may be difficult news for some AE patients, however at times it is comforting to know that what one suffers is not unusual. The study found that …

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Blood-brain barrier studies may lead to breakthrough in AE

We are encouraged that researchers at Columbia University Medical Center in NY, NY recently published a review article, bringing together many facets of research on how antibodies and other types of immune cells are able to cross the blood-brain barrier and gain access to the brain, causing autoimmune encephalitis. They stated that these routes of …

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A call for brain tissue samples

The following contains a sensitive request, and is a copy of a letter sent to medical professionals that are part of AEA’s Clinicians Network.  We, at AEA, thought that those who have connected with us over the years would want to see this extraordinary request. Please know that we treat such a call for samples with …

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Autoimmune encephalitis in psychiatric institutions: current perspectives

Authors Chloe Bost,Olivier Pascual, and Jérôme Honnorat published the following in Dove Press an open access peer-reviewed publication devoted to medical  and scientific research. Abstract: Autoimmune encephalitis is a rare and newly described group of diseases involving autoantibodies directed against synaptic and neuronal cell surface antigens. It comprises a wide range of neuropsychiatric symptoms. Sensitive and specific …

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