Category: Research

Incidence of AE estimated by Mayo study

Autoimmune encephalitis experts at the Mayo Clinic published the first population-based study of AE in an effort to determine the incidence of the disease. The researchers found that in the last decade approximately 1 in every 100,000 people develop AE each year. This translates into approximately 4,000 new AE cases in the US annually and …

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Long-term neurobehavioral outcomes in Autoimmune Encephalitis

One of the first studies on long-term neurobehavioral outcomes in patients affected by AE will be presented by Anusha Yeshokumar, MD, during the upcoming Encephalitis Society meeting in London. This may be difficult news for some AE patients, however at times it is comforting to know that what one suffers is not unusual. The study found that …

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Blood-brain barrier studies may lead to breakthrough in AE

We are encouraged that researchers at Columbia University Medical Center in NY, NY recently published a review article, bringing together many facets of research on how antibodies and other types of immune cells are able to cross the blood-brain barrier and gain access to the brain, causing autoimmune encephalitis. They stated that these routes of …

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A call for brain tissue samples

The following contains a sensitive request, and is a copy of a letter sent to medical professionals that are part of AEA’s Clinicians Network.  We, at AEA, thought that those who have connected with us over the years would want to see this extraordinary request. Please know that we treat such a call for samples with …

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Autoimmune encephalitis in psychiatric institutions: current perspectives

Authors Chloe Bost,Olivier Pascual, and Jérôme Honnorat published the following in Dove Press an open access peer-reviewed publication devoted to medical  and scientific research. Abstract: Autoimmune encephalitis is a rare and newly described group of diseases involving autoantibodies directed against synaptic and neuronal cell surface antigens. It comprises a wide range of neuropsychiatric symptoms. Sensitive and specific …

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New paper on antibodies and autoimmune encephalitis

Abstract Reprinted from Health and Human Services Author Manuscript – Over the last 10 years the continual discovery of novel forms of encephalitis associated with antibodies to cell-surface or synaptic proteins has changed the paradigms for diagnosing and treating disorders that were previously unknown or mischaracterized. We review here the process of discovery, the symptoms, …

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Paper examines frequency of herpes viruses in autoimmune encephalitis patients

In a new paper published in Neurology, an official journal of the American Academy of Neurology, Dr. Jenny J. Linnoila et al., “report the frequency of coexisting herpes viruses (herpes simplex virus 1 [HSV-1] or HSV-2, varicella zoster virus, Epstein-Barr virus [EBV], cytomegalovirus, or human herpes virus 6 [HHV-6]) andautoantibodies in patients with encephalitis (herpes or autoimmune) …

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Jill Littrell, Ph.D. explores neuroscience and physiological explanations behind diagnostic categories of mental illness

Jill Littrell’s new book, Neuroscience for Psychologists and Other Mental Health Professionals: Promoting Well-Being and Treating Mental Illness, presents the latest neuroscience and physiological explanations behind the major diagnostic categories of mental illness—including schizophrenia, depression, anxiety, and addiction—and explains the physiological bases that underlie traditional pharmaceutical treatment interventions.  Of particular note in the book is cutting-edge information …

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Your experience helps others find doctors that treat autoimmune encephalitis

  Did you know that the Autoimmune Encephalitis Alliance has a “Clinicians Network” which helps patients find doctors around the globe? We need your help expanding this network. If you are a patient, caregiver, family member, or physician and had a positive experience with a medical professional that treats AE, please write to him/her and ask that he/she …

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Dr. Luca Bartolini creates survey on best practices to treat anti-NMDA receptor encephalitis

The following information was provided by Neurology, the official journal of the American Academy of Neurology. In the absence of data from clinical trials, anecdotal experience and expert opinion become the main source of knowledge on which medical decisions are made to treat anti-NMDA encephalitis. Clinical approaches and decision-making are apt to change over time …

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