Anti-NMDA Receptor Encephalitis in Psychiatry

April 11, 2014

Anti-NMDA Receptor Encephalitis in Psychiatry
Kayser et al.
Curr Psychiatry Rev. 2011; 7(3):189-193.

“Anti-NMDA receptor encephalitis is an autoimmune disorder in which antibodies attack NMDA (N-methyl-D-aspartate)-type glutamate receptors at central neuronal synapses. Symptoms include a highly characteristic set of neurologic deficits, but also prominent psychiatric manifestations that often bring mental health professionals into the course of care. Distinct phases of illness have become increasingly appreciated, and include a range of psychotic symptoms early in the course of the disease followed by more severe fluctuations in consciousness with neurologic involvement, and ultimately protracted cognitive and behavioral deficits. We provide an up to date review of this disorder and highlight the role of psychiatry in diagnosis, symptomatology, and treatment.”

Abstract from