Research

Central nervous system neuronal surface antibody associated syndromes: review and guidelines for recognition Zuliani et al. J Neurol Neurosurg Psychiatry. 2012 June; 83(6): 638-645. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3348613/ The concept of antibody mediated CNS disorders is relatively recent. The classical CNS paraneoplastic neurological syndromes are thought to be T cell mediated, and the onconeural antibodies merely biomarkers for […]

The National Health Service of England published the following review of IVIg for treatment of autoimmune encephalitis. The report was released in January 2016. “Evidence Review: Intravenous immunoglobulin for autoimmune encephalitis” Autoimmune encephalitis (AIE) is used to describe a group of disorders characterised by symptoms of limbic and extra-limbic dysfunction occurring in association with antibodies […]

One of the one of the largest university hospitals in Europe, Charite’, recorded significant progress in treating anti-NMDAR, including in patients who did not previously respond to treatment. Anti-NMDA receptor encephalitis is an inflammatory disease that affects the central nervous system. It is a rare autoimmune disease that results in the body producing antibodies against […]

We would like to invite all AE patients and their caregivers to make a difference in research on the disease. Please click on the correct link below and join us in moving the research forward. The AE Alliance is honored to be participating in a study authored by Dr. Anusha Yekoshumar at The Icahn School […]

Researchers at Johns Hopkins University published a retrospective study in which they examined the PET scans of patients who had been definitively diagnosed with autoimmune encephalitis over a ten-year period. They compared patients with anti-NMDA receptor encephalitis with other subgroups. They found those with anti-NMDAr AE consistently showed abnormalities in the form of hypometabolism (lower […]

#GivingTuesdayNow on May 5, 2020, is a global day of generosity and unity, a day to come together and give back in response to the unprecedented need caused by COVID-19. AE Alliance will participate in Giving Tuesday Now and launch the AEA Research Network with webinars by Dr. Sean Pittock (Mayo Clinic) and Dr. Stanley […]

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2430743/

https://www.thieme-connect.com/DOI/DOI?10.1055/s-0031-1277985

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3348613/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3895328/