Category: Research

Autoimmune encephalitis: proposed best practice recommendations for diagnosis, acute-, symptomatic-, and long-term management.

We are excited to report the first international best practice recommendations for  the management of autoimmune encephalitis. The papers result from the hard work and collaboration between 68 AEA Clinicians Network members from 17 countries, initiated and led by Dr. Hesham Abboud. These recommendations will be of great value to AE patients and clinicians all …

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Neurologic syndromes related to anti-GAD65

Antibodies against glutamic-acid-decarboxylase 65 (anti-GAD65) are associated with several neurologic syndromes, including stiff person syndrome and limbic encephalitis. However, their pathogenic role remains controversial. A group led by Dr. Maarten Titulaer (Erasmus University, the Netherlands) studied the clinical relevance of different anti-GAD65 concentrations in patients with neurological disorders and their response to treatment. The group …

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How coronavirus affects the brain

Since December 2019, almost 13.5 million cases and 581,103 deaths due to the coronavirus have been reported worldwide, according to the Johns Hopkins Coronavirus Resource Center. There are many papers published on COVID-19 and its consequences, and we, at AE Alliance, are especially interested in how the coronavirus affects the brain. We wanted to share …

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Evaluation of seizure treatment in AE

In this nationwide cohort study, by De Bruijn and colleagues, the authors evaluated the seizure responses to immunotherapy and anti-epileptic drugs (AED’s) in patients with NMDAR, LGI1, and GABAbR encephalitis. The study included 153 patients with AE (53 LGI1, 75 NMDAR, 25 GABABR). Of those, 110 patients had epileptic seizures and were included in the …

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