Research
Dale et al Brain. 2012 Nov;135(Pt11):3453-68. https://academic.oup.com/brain/article/135/11/3453/272463 Recent reports of autoantibodies that bind to neuronal surface receptors or synaptic proteins have defined treatable forms of autoimmune encephalitis. Despite these developments, many cases of encephalitis remain unexplained. We have previously described a basal ganglia encephalitis with dominant movement and psychiatric disease, and proposed an autoimmune aetiology. […]
A clinical approach to diagnosis of autoimmune encephalitis Graus F, Titulaer MJ, et al. Lancet Neurology 2016 Apr; 15(4):391-404 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5066574/ Encephalitis is a severe inflammatory disorder of the brain with many possible causes and a complex differential diagnosis. Advances in autoimmune encephalitis research in the past 10 years have led to the identification of new […]
It is often difficult to clinically diagnosis autoimmune encephalitis because patients’ symptoms can be so widely varied. In the Sept. 2016, issue of The Lancet Neurology, Francesc Graus and colleagues proposed an initial diagnostic work-up relying on conventional neurological evaluation and standard diagnostic tests such as MRI, CSF sampling, and EEG. This approach would enable clinicians to make […]
One of our goals at the AE Alliance is to distribute high-quality educational information for all who are touched by the illness. We have compiled a list of about a dozen articles that may be of interest. This is not an exhaustive list; it is merely a sampling of the main articles published on AE. […]
A group of physicians from Germany have recently published an article in Seminars in Immunopathology, noting significant differences in the incidence of autoimmune diseases of the central nervous system in males versus females. They stated diseases such as multiple sclerosis, neuromyelitis optica and autoimmune encephalitis are more likely to be found in females. Some examples […]
Dr. Sean Pittock and his group at Mayo Clinic Rochester recently completed a clinical trial that was co-sponsored by the AE Alliance. The study evaluated IVIG treatment in patients with autoimmune epilepsy who fail to benefit from standard epilepsy medications and/or for those where corticosteroids are not considered a treatment option. Last week, in a […]
https://journals.lww.com/theneurologist/Abstract/2007/09000/Limbic_Encephalitis_and_Variants__Classification,.3.aspx
https://academic.oup.com/qjmed/article/104/11/921/1563094
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3718498/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3806918/