Dr. Amanda Piquet – CAR T Therapy for Autoimmune Disease

October 21, 2024

Many thanks to Dr. Amanda Piquet, Board of Directors & Medical Advisory Board Member, Autoimmune Encephalitis Alliance for speaking at our November 2024 AEA Provider Monthly Education Series and presenting CAR T Therapy for Autoimmune Disease.

We discussed the background of the CAR T therapy and its more recent use in  autoimmune disease. We also discussed current examples of how this is being explored in neurologic disorders such as Stiff Person Syndrome.


Review relevant references for the session:

  1. Müller F, Taubmann J, Bucci L, Wilhelm A, Bergmann C, Völkl S, Aigner M, Rothe T, Minopoulou I, Tur C, Knitza J, Kharboutli S, Kretschmann S, Vasova I, Spoerl S, Reimann H, Munoz L, Gerlach RG, Schäfer S, Grieshaber-Bouyer R, Korganow AS, Farge-Bancel D, Mougiakakos D, Bozec A, Winkler T, Krönke G, Mackensen A, Schett G. CD19 CAR T-Cell Therapy in Autoimmune Disease – A Case Series with Follow-up. N Engl J Med. 2024 Feb 22;390(8):687-700. doi: 10.1056/NEJMoa2308917. PMID: 38381673.
  2. Hay KA, Turtle CJ. Chimeric Antigen Receptor (CAR) T Cells: Lessons Learned from Targeting of CD19 in B-Cell Malignancies. Drugs. 2017 Mar;77(3):237-245. doi: 10.1007/s40265-017-0690-8. PMID: 28110394; PMCID: PMC5603178.


The AEA Monthly Didactic + Case Discussion series benefits greatly from the invaluable contributions of our committed autoimmune encephalitis experts. These professionals volunteer their precious time, sharing their profound wisdom and enriching our understanding. Their expertise not only enhances our knowledge but also makes a measurable impact on everyone present. We sincerely acknowledge their contributions.

Learn more about Dr. Piquet.

Learn more about the AEA Provider Monthly Didactic + Case Discussion Series.

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