Dr. Hesham Abboud – Symptomatic Management of Autoimmune Encephalitis
March 3, 2025
Many thanks to Dr. Hesham Abboud, MD, PhD, for joining our May 2025 AEA Provider Monthly Education Series and presenting on symptomatic management of autoimmune encephalitis.
Dr. Abboud is the Director of Neuroimmunology at University Hospitals Cleveland Medical Center and Associate Professor of Neurology at Case Western Reserve University. He founded and currently runs a specialized autoimmune encephalitis clinic and a busy inpatient consultation service for autoimmune neurological patients at University Hospitals of Cleveland.
Learning objectives of the session:
Learn the most common presenting and residual symptoms of autoimmune encephalitis
Learn therapeutic approaches to symptomatic management of autoimmune encephalitis in the acute and recovery phases of the disease
Identify the knowledge gaps and pressing needs in autoimmune encephalitis symptom management
Links to relevant references:
Abboud H, Probasco J, Irani SR, et al., Autoimmune Encephalitis Alliance Clinicians Network. Autoimmune encephalitis: proposed recommendations for symptomatic and long-term management. J Neurol Neurosurg Psychiatry. 2021 Mar 1;92(8):897–907. doi: 10.1136/jnnp-2020-325302. Epub ahead of print. PMID: 33649021; PMCID: PMC8292591.
Matricardi S, Casciato S, Bozzetti S, et al., Immune Epilepsies Study Group of the Italian League Against Epilepsy. Epileptic phenotypes in autoimmune encephalitis: from acute symptomatic seizures to autoimmune-associated epilepsy. J Neurol Neurosurg Psychiatry. 2022 Jul 25:jnnp-2022-329195. doi: 10.1136/jnnp-2022-329195. Epub ahead of print. PMID: 35879055.
Ali F, Wijdicks EF. Treatment of Movement Disorder Emergencies in Autoimmune Encephalitis in the Neurosciences ICU. Neurocrit Care. 2020 Feb;32(1):286-294. doi: 10.1007/s12028-019-00875-5. PMID: 31732848.
Mohammad SS, Jones H, Hong M, Nosadini M, Sharpe C, Pillai SC, Brilot F, Dale RC. Symptomatic treatment of children with anti-NMDAR encephalitis. Dev Med Child Neurol. 2016 Apr;58(4):376-84. doi: 10.1111/dmcn.12882. Epub 2015 Aug 28. PMID: 26330176.
Thakolwiboon S, Gilligan M, Orozco E, et al., Autoimmune encephalitis: recovery, residual symptoms and predictors of long-term sequelae. J Neurol Neurosurg Psychiatry. 2025 Jan 19:jnnp-2024-334957. doi: 10.1136/jnnp-2024-334957. Epub ahead of print. PMID: 39832911.
Abboud H, Briggs F, Buerki R, et al., Residual symptoms and long-term outcomes after all-cause autoimmune encephalitis in adults. J Neurol Sci. 2022 Mar 15;434:120124. doi: 10.1016/j.jns.2021.120124. Epub 2021 Dec 31. PMID: 34998237.
The AEA Monthly Didactic + Case Discussion series benefits greatly from the invaluable contributions of our committed autoimmune encephalitis experts. These professionals volunteer their precious time, sharing their profound wisdom and enriching our understanding. Their expertise not only enhances our knowledge but also makes a measurable impact on everyone present. We sincerely acknowledge their contributions.