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Comparing autoantibody-negative and autoantibody-positive Autoimmune Encephalitis patients

Early diagnosis of AE allows for aggressive treatment, which greatly improves recovery outcomes. On the contrary, delayed diagnosis and treatment can lead to permanent brain injury or even loss of life. In literature, no work has been published which compares clinical, radiological and laboratory characteristics of patients with definite autoantibody-positive AE (AE+) and autoantibody-negative AE (AE-). …

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The psychopathology of NMDAR-antibody encephalitis in adults

A group of researchers from the Autoimmune Neurology Group at the University of Oxford led by Dr. Sarosh Irani,  recently published an article in the Lancet Psychiatry, noting that a focus on the psychopathology is likely the most effective way to promote prompt recognition of NMDAR-antibody encephalitis. NMDAR-antibody encephalitis is an autoantibody-mediated disease that typically presents …

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Psychiatrists play a pivotal role in the diagnosis and treatment of AE

Psychiatrists play a pivotal role in the diagnosis and treatment of AE. As psychiatric symptoms often dominate the symptoms that occur at onset of this disease, patients may present initially to a psychiatrist who are tasked with identifying abnormal features of psychosis presentations, including alterations in mental status, seizures, and dysautonomia, which may prompt consideration …

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Oxford Autoimmune Neurology Meeting 2019

This is a two-day international meeting on 5-6 June 2019 for clinicians and scientists looking to appreciate the breadth of translational autoimmune neurology. This inaugural meeting will cover the clinical features of CNS and PNS diseases, methodological aspects of immunological assays, applied T and B cell pathophysiology, and questions relating to immunological tolerance. By being …

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